CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin
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چکیده
منابع مشابه
CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin.
Recently, we reported that extracellular ubiquitin functions as another agonist of CXC chemokine receptor (CXCR)4. Whereas the cognate CXCR4 ligand, stromal cell-derived factor (SDF)-1α, is also a CXCR7 agonist, ubiquitin does not bind to CXCR7. Because both ligands are present in the extracellular environment, co-activation of CXCR4 appears to be physiologically relevant. CXCR4 mediated effect...
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ژورنال
عنوان ژورنال: Cytokine
سال: 2014
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2013.12.008